scientist in north chicago

posted
job type
permanent
salary
US$ 68 per year
apply now

job details

posted
location
north chicago, illinois
job category
Biotechnology & Pharmaceutical
job type
permanent
salary
US$ 68 per year
reference number
25532
apply now

job description

Job Title: Senior Scientist, Chemical Engineer

Position Description

  • Department: Research & Development
  • This department invents synthetic processes to prepare active pharmaceutical ingredients (APIs) to enable the development of the company's pipeline, and ultimately to provide commercial manufacturing processes.
  • Our Client is seeking a highly motivated individual with a proven track record of accomplishment to join the API Pilot Plant Technical Operations (Tech Ops) group. This position will serve as a liaison between the Process Research and Development scientific functions and the API Pilot Plant organization.
  • The successful candidate will assist in the optimization and scale-up of synthetic processes and facilitate the implementation of the processes and new technologies in to the API Pilot Plant.
  • The Scientist will also provide technical oversight during production campaigns and will support technical transfer to the ultimate commercial manufacturing site.

Position Responsibilities

  • Management of processes entering the API Pilot Plant, including scheduling, equipment selection, materials tracking, authoring direction sets, obtaining safety analyses, and executing pre-runs.
  • Technical oversight of processes running in the API Pilot Plant, and responsibility for process-trouble shooting in collaboration with the project teams.
  • Serves as primary point of contact between API Pilot Plant, project teams, Quality Assurance, and Environmental Health and Safety.
  • Responsible for review and documentation of data for cGMP execution of chemical processes. Authors campaign summary reports.
  • Identify, evaluate and implement new technologies for the pilot plant and/or identify opportunities to modify or leverage existing assets to enhance operational efficiency. Examples include automation, flow chemistry, novel separation, Process Analytical Technology (PAT) feedback control and drying technologies.
  • Support the implementation of PAT. Assist with equipment specification, setup, data collection and analysis.
  • Interface with project teams to ensure that processes are safe and operable.
  • Partner with API development teams to optimize processes for scale-up. Identify appropriate equipment and configurations.
  • Assist with technology transfer of late stage processes to commercial sites, including process fit, identification of equipment needs, and facility modifications.

Position Requirements

Basic

  • BS, MS, PhD in Chemical Engineering with 14+ (BS), 12+ (MS), or 6+ (PhD) years of experience
  • 3 Years (minimum) in drug substance development
  • Understanding of cGMP, process safety requirements, and OSHA chemical hygiene plans.
  • Working Knowledge of analytical techniques such as HPLC, GC, NMR, and microscopy
  • Experience with Process Analytical Technology

Preferred

  • Experience with laboratory experiments, process scale-up from lab to pilot plant and/or transferring a process from pilot plant to a commercial facility.
  • Experience working in an API Plant environment, familiarity with operation of chemical process equipment and systems.
  • Strong technical background in chemical processing unit operations including reactions, crystallization, distillation, extraction, membrane separation, chromatography, centrifugation, filtration, drying and milling.

Benefits

  • Full Package with possible relocation

Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.