5 jobs found in Geneva, Genève

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    • geneva, genève
    • permanent
    Willing to join one innovative biotech company in the heart of Geneva? Willing to drive the development of recombinant mammalian cell lines?Your tasks:You shall ensure efficient operation of single-use bioreactors for the production of therapeutic proteins with mammalian expression systems. Mainly, - Understand and execute Ambr15 micro bioreactors procedures with a specific focus on evaluation of high producing mammalian cell lines,- Support Upstream Process (USP) team in routine cell culture laboratory activities   (main cultivation, inoculation, harvest),- Execute experimental processes according to pre-established plans, timelines and  priorities,- Record and analyze sample data, verify data integrity and provide technical reports,- Participate to troubleshooting activities and process improvement of USP processes,- Ensure scientifically scale-up and scale-down of USP activities,- Maintain equipment needed to carry out assignments following established protocols.This position will require engagement to work on weekends (weekend call-outs and operating at distance or on site if necessary).You bring: • Bachelor in biochemistry, chemistry, biology or equivalent,• Minimum 3 years relevant industry experience in USP process development or Cell   Line Development,• Practical experience with USP equipment (shake flasks, single-use bioreactors of different scales from 15mL to multiliters, e.g. Ambr15, 2L bioreactors),• Relevant experience in cell culture and aseptic/sterile techniques,• Bilingual in French and English.
    Willing to join one innovative biotech company in the heart of Geneva? Willing to drive the development of recombinant mammalian cell lines?Your tasks:You shall ensure efficient operation of single-use bioreactors for the production of therapeutic proteins with mammalian expression systems. Mainly, - Understand and execute Ambr15 micro bioreactors procedures with a specific focus on evaluation of high producing mammalian cell lines,- Support Upstream Process (USP) team in routine cell culture laboratory activities   (main cultivation, inoculation, harvest),- Execute experimental processes according to pre-established plans, timelines and  priorities,- Record and analyze sample data, verify data integrity and provide technical reports,- Participate to troubleshooting activities and process improvement of USP processes,- Ensure scientifically scale-up and scale-down of USP activities,- Maintain equipment needed to carry out assignments following established protocols.This position will require engagement to work on weekends (weekend call-outs and operating at distance or on site if necessary).You bring: • Bachelor in biochemistry, chemistry, biology or equivalent,• Minimum 3 years relevant industry experience in USP process development or Cell   Line Development,• Practical experience with USP equipment (shake flasks, single-use bioreactors of different scales from 15mL to multiliters, e.g. Ambr15, 2L bioreactors),• Relevant experience in cell culture and aseptic/sterile techniques,• Bilingual in French and English.
    • geneva, genève
    • permanent
    Willing to join one innovative biotech company in the heart of Geneva? Willing to drive the development of recombinant mammalian cell lines?Your tasks:This position will be shared between two departments, Analytics and DownStream Process (DSP) departments. Under the supervision of staff analytic engineers, you will:- Support analytics team in routine analytics laboratory activities,- Understand and execute analytical procedures with a specific focus on      routine testing,- Understand protein sample type and format, purpose of test assay and be capable to design appropriately,- Record and analyze sample data, verify data integrity and provide technical reports,- Develop the ability of troubleshooting and problem solving with scientific guidance,- Handle simple equipment maintenance following established protocols,- Maintain equipment needed to carry out assignments following established protocols. Under the supervision of staff DSP engineers, you will:- Carry out routine protein purification in support to DSP team,- Participate to the design of experiments, execute the planned experiments and optimize process steps,- Record and analyze sample data, verify data integrity and provide technical reports,- Initiate novel process/technology when applicable,- Maintain equipment needed to carry out assignments following established Protocols.You bring: • Bachelor in biochemistry, chemistry, biology or equivalent,• 1-5 years’ experience in the pharmaceutical or biotechnology field is preferred,• Direct experience with basic and advanced analytical procedures (ELISA, SDS-PAGE,     westernblot, iCIEF, CE-SDS, SEC-HPLC, Protein A HPLC),• Direct experience with DownStream Process (DSP) activities (clarification, purification by chromatography or using magnetic beads, diafiltration),• Familiarity with various modes of purification (column chromatography, magnetic beads),• Bilingual in French and English.
    Willing to join one innovative biotech company in the heart of Geneva? Willing to drive the development of recombinant mammalian cell lines?Your tasks:This position will be shared between two departments, Analytics and DownStream Process (DSP) departments. Under the supervision of staff analytic engineers, you will:- Support analytics team in routine analytics laboratory activities,- Understand and execute analytical procedures with a specific focus on      routine testing,- Understand protein sample type and format, purpose of test assay and be capable to design appropriately,- Record and analyze sample data, verify data integrity and provide technical reports,- Develop the ability of troubleshooting and problem solving with scientific guidance,- Handle simple equipment maintenance following established protocols,- Maintain equipment needed to carry out assignments following established protocols. Under the supervision of staff DSP engineers, you will:- Carry out routine protein purification in support to DSP team,- Participate to the design of experiments, execute the planned experiments and optimize process steps,- Record and analyze sample data, verify data integrity and provide technical reports,- Initiate novel process/technology when applicable,- Maintain equipment needed to carry out assignments following established Protocols.You bring: • Bachelor in biochemistry, chemistry, biology or equivalent,• 1-5 years’ experience in the pharmaceutical or biotechnology field is preferred,• Direct experience with basic and advanced analytical procedures (ELISA, SDS-PAGE,     westernblot, iCIEF, CE-SDS, SEC-HPLC, Protein A HPLC),• Direct experience with DownStream Process (DSP) activities (clarification, purification by chromatography or using magnetic beads, diafiltration),• Familiarity with various modes of purification (column chromatography, magnetic beads),• Bilingual in French and English.
    • geneva, genève
    • temporary
    Do you have a significant experience in project management defining strategy for different project development phase and therapeutic areas?Did you already lead cross functional teams in a global matrix environment?Are you known for your resilience and optimism, and looking for your next challenge?In this case, you should have a look at this opportunity!Our client, an international biotechnology industry based in the Geneva area, is looking for a:Director Global Project Lead (temporary contract - from September 2021 to March 2022) Functional Goal:Lead cross-functional development teams, define the program strategy in alignment with relevant governance bodies and supervise Project Managers in the execution of global development programs for the Biosimilar Unit. Lead the definition and implementation of the Target Product Profile with relevant functions and the overall product development strategy (integrated Development Plan, iDP). Lead the Global Program Leadership activities for several projects ensuring high standards of performance of the project teams and its individual members. By its central role for the programs, the person in charge is expected to make a critical contribution to the success of the Unit.Assume accountability for the delivery of either early or late stage projects from strategic perspective. Drive and lead the project teams from a strategic stand point. Provide critical cross-functional input into project strategy and ensure cohesion of the early or late stage project activities. Lead Project strategic initiatives.As member of the leadership team of the Program  Leadership and Managemnet  function, contribute to the strategy of the function.Act as deputy to Head of Program Leadership and Management when senior leadership input/attendance at meetings is required.Main Tasks:Key accountability:Define and get approved the strategy of either early or late stage portfolio in alignment with relevant government bodies. Active contribution in portfolio decisions.Accountable for driving the valuation of early or late stage projects, including external opportunities, leading the creation of assumptions and the alignment for project evaluation.Set priorities for either early or late stage project activities, escalate resource conflicts and contribute to resolution. Align resources needs and prioritization with government bodies. Drive definition of robust and focused Target Product Profiles (TPP) together with commercial function, generate comprehensive and consistent strategic development plans (iDP) with program team, drive definition of regulatory dossier strategy plans together with regulatory function. Contribute to the creation of storyline and key messages for the regulatory submissions (dossier and consultations); work with the regulatory lead to develop a global submission strategy; align the full development team to agreed strategy.Remain abreast of new developments in the biosimilar field, and contribute to building business insight and knowledge within the Biosimilars teamEnsure optimal steering of processes, and contribute to improvement of systems (processes, tools).Financial Dimension:Program budget accountability for several development projects.Prioritize program activities in line with the approved program strategy and plans; align resource needs with the biosimilar leadership members.Strategic Impact:Leading the development team, define the program strategy and driving the implementation of a global development program for the biosimilar unit with substantial impact on the success of the program and therefore the success of the whole unit.Preparation, creation:Drive development of a Target Product Profile (TPP).Based on the TPP, lead definition of development strategy, summarized in an iDP and ensure governance committee approval.Lead the development and the approval of a QTTP as quality target for the product.Execution:Lead Biosimilar Program Team (s) to ensure accountability and performance of the team and each function representative.Make necessary decisions for the product within the frame of the approved strategy or escalate to the governance committee if appropriate.Communicate transparently risk (changes in the risk profile), mitigations and options to ensure alignment of the Biosimilar unit behind the product strategy.Lead the creation of storyline and key messages for the regulatory dossier; work with the regulatory lead to develop a global submission strategy including submission plan.Support: Leading Portfolio Evaluation at project level.Support Business Development and Alliance Management in evaluation of opportunities and due diligence activities and in maintaining efficient working relationships with external partners.Cooperation with internal and external stakeholders:All members of the biosimilars governance committees and functions represented in the Project Team.Head of functions within biosimilar unit.R&D, Controlling, Finance, Portfolio, Manufacturing.Regulatory agencies; CROs, CMO and licensing partners. Qualification profile:Education:Advanced scientific/business degree with 10+ years’ experience in biopharma/biotech industry.Competencies and skills:Excellent organizational skills a must.Strategic orientation, leadership and management competencies (problem solving, influencing and decision making, driving teams to deliverables, …)Entrepreneurial spirit and action/results driven.Ability to critically evaluate scientific data obtained at different stages of development.Excellent communication skills, both oral and written.Strong interpersonal, networking and relationship skills required.Dynamic, energetic and positive mindset.Must be proficient with Microsoft Office programs and project management tools & concepts.Languages:Fluency in English essential, both oral and written; additional languages (German or French) are an asset.Work experience:Seniority in Program Leadership with minimum 5 years on complex projects having dealt with different project development phase and therapeutic areas.Demonstrated success operating in a global matrix organization with the full breadth of functions contributing to drug development.Experienced working in the field of biosimilars or biologics.Advanced knowledge of project management principles.if you recognize yourself in this ad, don't wait any longer and apply now! 
    Do you have a significant experience in project management defining strategy for different project development phase and therapeutic areas?Did you already lead cross functional teams in a global matrix environment?Are you known for your resilience and optimism, and looking for your next challenge?In this case, you should have a look at this opportunity!Our client, an international biotechnology industry based in the Geneva area, is looking for a:Director Global Project Lead (temporary contract - from September 2021 to March 2022) Functional Goal:Lead cross-functional development teams, define the program strategy in alignment with relevant governance bodies and supervise Project Managers in the execution of global development programs for the Biosimilar Unit. Lead the definition and implementation of the Target Product Profile with relevant functions and the overall product development strategy (integrated Development Plan, iDP). Lead the Global Program Leadership activities for several projects ensuring high standards of performance of the project teams and its individual members. By its central role for the programs, the person in charge is expected to make a critical contribution to the success of the Unit.Assume accountability for the delivery of either early or late stage projects from strategic perspective. Drive and lead the project teams from a strategic stand point. Provide critical cross-functional input into project strategy and ensure cohesion of the early or late stage project activities. Lead Project strategic initiatives.As member of the leadership team of the Program  Leadership and Managemnet  function, contribute to the strategy of the function.Act as deputy to Head of Program Leadership and Management when senior leadership input/attendance at meetings is required.Main Tasks:Key accountability:Define and get approved the strategy of either early or late stage portfolio in alignment with relevant government bodies. Active contribution in portfolio decisions.Accountable for driving the valuation of early or late stage projects, including external opportunities, leading the creation of assumptions and the alignment for project evaluation.Set priorities for either early or late stage project activities, escalate resource conflicts and contribute to resolution. Align resources needs and prioritization with government bodies. Drive definition of robust and focused Target Product Profiles (TPP) together with commercial function, generate comprehensive and consistent strategic development plans (iDP) with program team, drive definition of regulatory dossier strategy plans together with regulatory function. Contribute to the creation of storyline and key messages for the regulatory submissions (dossier and consultations); work with the regulatory lead to develop a global submission strategy; align the full development team to agreed strategy.Remain abreast of new developments in the biosimilar field, and contribute to building business insight and knowledge within the Biosimilars teamEnsure optimal steering of processes, and contribute to improvement of systems (processes, tools).Financial Dimension:Program budget accountability for several development projects.Prioritize program activities in line with the approved program strategy and plans; align resource needs with the biosimilar leadership members.Strategic Impact:Leading the development team, define the program strategy and driving the implementation of a global development program for the biosimilar unit with substantial impact on the success of the program and therefore the success of the whole unit.Preparation, creation:Drive development of a Target Product Profile (TPP).Based on the TPP, lead definition of development strategy, summarized in an iDP and ensure governance committee approval.Lead the development and the approval of a QTTP as quality target for the product.Execution:Lead Biosimilar Program Team (s) to ensure accountability and performance of the team and each function representative.Make necessary decisions for the product within the frame of the approved strategy or escalate to the governance committee if appropriate.Communicate transparently risk (changes in the risk profile), mitigations and options to ensure alignment of the Biosimilar unit behind the product strategy.Lead the creation of storyline and key messages for the regulatory dossier; work with the regulatory lead to develop a global submission strategy including submission plan.Support: Leading Portfolio Evaluation at project level.Support Business Development and Alliance Management in evaluation of opportunities and due diligence activities and in maintaining efficient working relationships with external partners.Cooperation with internal and external stakeholders:All members of the biosimilars governance committees and functions represented in the Project Team.Head of functions within biosimilar unit.R&D, Controlling, Finance, Portfolio, Manufacturing.Regulatory agencies; CROs, CMO and licensing partners. Qualification profile:Education:Advanced scientific/business degree with 10+ years’ experience in biopharma/biotech industry.Competencies and skills:Excellent organizational skills a must.Strategic orientation, leadership and management competencies (problem solving, influencing and decision making, driving teams to deliverables, …)Entrepreneurial spirit and action/results driven.Ability to critically evaluate scientific data obtained at different stages of development.Excellent communication skills, both oral and written.Strong interpersonal, networking and relationship skills required.Dynamic, energetic and positive mindset.Must be proficient with Microsoft Office programs and project management tools & concepts.Languages:Fluency in English essential, both oral and written; additional languages (German or French) are an asset.Work experience:Seniority in Program Leadership with minimum 5 years on complex projects having dealt with different project development phase and therapeutic areas.Demonstrated success operating in a global matrix organization with the full breadth of functions contributing to drug development.Experienced working in the field of biosimilars or biologics.Advanced knowledge of project management principles.if you recognize yourself in this ad, don't wait any longer and apply now! 
    • genève, genève
    • permanent
    Vous êtes médecin pathologue et vous recherchez un nouveau défi en tant que salarié ou indépendant? Nous recherchons pour notre client, un laboratoire d'analyses biologiques et pathologiques, situé au coeur de Genève un médecin pathologue à temps plein. Vous allez travailler en forte collaboration avec les techniciens anapathes. Vous êtes spécilialisé(e) dans les domaines de la gynécologie, la gastrologie et l'urologie mais plus particulièrement la cytologie gynécologique. Vous êtes la personne qui a la dernière responsabilité sur les analyses. Vous avez quelques années d'expérience dans ce domaine.Si vous êtes intéressé(e) par cette fonction et que vous correspondez au profil, n'hésitez pas à postuler. 
    Vous êtes médecin pathologue et vous recherchez un nouveau défi en tant que salarié ou indépendant? Nous recherchons pour notre client, un laboratoire d'analyses biologiques et pathologiques, situé au coeur de Genève un médecin pathologue à temps plein. Vous allez travailler en forte collaboration avec les techniciens anapathes. Vous êtes spécilialisé(e) dans les domaines de la gynécologie, la gastrologie et l'urologie mais plus particulièrement la cytologie gynécologique. Vous êtes la personne qui a la dernière responsabilité sur les analyses. Vous avez quelques années d'expérience dans ce domaine.Si vous êtes intéressé(e) par cette fonction et que vous correspondez au profil, n'hésitez pas à postuler. 
    • genève, genève
    • temporary
    Are you an expert in mass spectrometry and characterization of monoclonal antibodies or proteins? Are you recognized for your analytical an organizational skills?Are you available immediately or soon and looking for your next challenging position?In this case, you should have a look at this opportunity!Our client, an international biotechnology industry based in the Geneva area is looking for an:Associate Scientist / Scientist in Mass Spectrometry(1 year temporary contract - to start ASAP)Your main responsibilities:Analysis of protein biotherapeutics as part of the Mass Spectrometry &Process Analytics team.Technical operation of LC-MS and associated equipment with full datainterpretation to ensure accurate results are provided against plannedtimelines to support CMC development of Antibody products.Your tasks:• Perform weekly LC-MS calibration and maintenance• Responsible for mass spectrometry data generated in support of process and analytical teams.• Run platforms methods: LC-MS and LC-MS/MS routine testing techniques such as: Amino Acid Sequencing, Post-Translational Modification Analysis, Intact Molecular Weight Analysis, Glycosylation Mapping, Disulfide Bonding Pattern Analysis.• Ensure data traceability within the R&D IT infrastructure (use of eLN/LIMS, and monitor SST for each LC-MS method, etc).• Keep abreast of technical development to maintain a state-of-the-arttechnology platform.• Coordinate planning in MS laboratories to provide results and datainterpretation to project teams.• Build strong relationships and a collaborative network with all groups (USP, DSP, CLD, NPB and PCAO).• Provide support to Physicochemical analytics department to effectivelycommunicate data and plans within a cross functional organisation.Your profile:Education & work experience:• CFC or equivalent + 5-10 years of experience in mass spectrometry andprotein chemistry or Master’s degree with 2-3 years of experience in massspectrometry and protein chemistry.Skills:• Solid experience in protein analytics in the pharma or biotech industry.• Strong technical skills in laboratory.• Comfortable working within multidisciplinary Teams under tight timelines.• Results orientation and strategic thinking.• Excellent communication, presentation, and interpersonal skills.Languages:• Fluency in English essential, both oral and written; French would be an assetIf you recognize yourself in this ad, don't wait any longer and apply now!
    Are you an expert in mass spectrometry and characterization of monoclonal antibodies or proteins? Are you recognized for your analytical an organizational skills?Are you available immediately or soon and looking for your next challenging position?In this case, you should have a look at this opportunity!Our client, an international biotechnology industry based in the Geneva area is looking for an:Associate Scientist / Scientist in Mass Spectrometry(1 year temporary contract - to start ASAP)Your main responsibilities:Analysis of protein biotherapeutics as part of the Mass Spectrometry &Process Analytics team.Technical operation of LC-MS and associated equipment with full datainterpretation to ensure accurate results are provided against plannedtimelines to support CMC development of Antibody products.Your tasks:• Perform weekly LC-MS calibration and maintenance• Responsible for mass spectrometry data generated in support of process and analytical teams.• Run platforms methods: LC-MS and LC-MS/MS routine testing techniques such as: Amino Acid Sequencing, Post-Translational Modification Analysis, Intact Molecular Weight Analysis, Glycosylation Mapping, Disulfide Bonding Pattern Analysis.• Ensure data traceability within the R&D IT infrastructure (use of eLN/LIMS, and monitor SST for each LC-MS method, etc).• Keep abreast of technical development to maintain a state-of-the-arttechnology platform.• Coordinate planning in MS laboratories to provide results and datainterpretation to project teams.• Build strong relationships and a collaborative network with all groups (USP, DSP, CLD, NPB and PCAO).• Provide support to Physicochemical analytics department to effectivelycommunicate data and plans within a cross functional organisation.Your profile:Education & work experience:• CFC or equivalent + 5-10 years of experience in mass spectrometry andprotein chemistry or Master’s degree with 2-3 years of experience in massspectrometry and protein chemistry.Skills:• Solid experience in protein analytics in the pharma or biotech industry.• Strong technical skills in laboratory.• Comfortable working within multidisciplinary Teams under tight timelines.• Results orientation and strategic thinking.• Excellent communication, presentation, and interpersonal skills.Languages:• Fluency in English essential, both oral and written; French would be an assetIf you recognize yourself in this ad, don't wait any longer and apply now!

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