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    • neuchâtel, neuchâtel
    • temporary
    Do you have experience in product testing ? Do you like to evolve in the medical device industry ? Have a look below then!One of our clients, specialised in medical devices and based in the Neuchâtel area, is looking for a R&D Technician for a 1 year contract (possibility of extension).Your tasks:Perform product verification/validation testingOrganize collected DataAnalyze dataDebug test fixtures if problems occur Your profile:Minimum 3 years of industry experienceExperience in product testingTest set up debugging,Good communication skillsCollege degree is a plusExperience working for medical device industry is a plusUnderstanding of basic fluidicsFluent in French and English Do you recognize yourself in those lines ? Then apply now without waiting any second!
    Do you have experience in product testing ? Do you like to evolve in the medical device industry ? Have a look below then!One of our clients, specialised in medical devices and based in the Neuchâtel area, is looking for a R&D Technician for a 1 year contract (possibility of extension).Your tasks:Perform product verification/validation testingOrganize collected DataAnalyze dataDebug test fixtures if problems occur Your profile:Minimum 3 years of industry experienceExperience in product testingTest set up debugging,Good communication skillsCollege degree is a plusExperience working for medical device industry is a plusUnderstanding of basic fluidicsFluent in French and English Do you recognize yourself in those lines ? Then apply now without waiting any second!
    • basel, basel-stadt
    • temporary
    For our client, a leading pharmaceutical company in Rotkreuzm we are looking for a :Scientist in immunology This role sits within pRED in Immunology Discovery, part of the Immunology, Infections Diseases and Ophthalmology (I2O) Department, located in Basel, Switzerland. We are seeking an independent and highly motivated researcher to advance our understanding of the mechanisms underlying the progression of inflammatory bowel diseases (IBD).Specifically, the research project will aim at investigating the role of T cell plasticity in maintaining intestinal homeostasis and in the development of chronic and tissue-damaging intestinal inflammation. In addition the relationship between T cell plasticity and intestinal microbiota will be a central element of this project. Profile:To cover for a maternity leave, we are looking for a scientist with education in immunology (PhD are preferred, Master or Post Doc are considered). This person needs to have experience in human immunology, cell biology and flow cytometry. Please note experience in human immunology is a must.General Information:• Start date: ASAP• Latest possible start date: 1 month notice period max• End date: 9 months duration• Extension: possible• Workplace: Basel• Workload: 100%• Remote/Home Office: Onsite needed, certificate will be required. Mostly onsite.• Travel: No• Team: Around 3 peopleTasks & Responsibilities:• Develop methods for isolation of immune cells from blood and tissue;• Perform detailed immune phenotyping of cell populations of interest using multicolormulti-color flow cytometry;• Perform sophisticated in vitro 3D cultures, including organoids, of human and mouse cells;• Investigate the impact of bacterial isolates and/or metabolites on host immune, epithelial and stromal cells;• In collaboration with data scientists, analyze multi omics data sets including scRNAseq, TCRseq, 16Sseq,metabolomics and identify molecules to be tested in vitro;• Carry out in vivo studies to further mechanistic understanding;• Form close collaborative relationships with other scientists within the Immunology Incubator, I2O Department andtechnical teams in other functions.Must Haves:• Min Master, preference on PhD in immunology (*****)• Profound understanding of human immunology, mucosal immunity and T cell biology. (*****)• Extensive experience with state-of-the-art flow cytometry, including FACS. (*****)• Track record of hands-on experience with isolation and cultivation of human immune cells. (*****)• Experience with in vivo models of inflammation is a plus.• Experience in data analysis using R or Python is a plus.• You have very good interpersonal and communication skills, are able to build good working relationships and are anoutstanding teammate.• Your experience and investigative attitude allow you to work independently, to design, perform and interpretexperiments and to embark on new scientific methodologies.• You published as a leading author in top-tier journals.• You have a strong team spirit, and you like to work in international teams• Your excellent English skills, written and spoken, complete your profile.
    For our client, a leading pharmaceutical company in Rotkreuzm we are looking for a :Scientist in immunology This role sits within pRED in Immunology Discovery, part of the Immunology, Infections Diseases and Ophthalmology (I2O) Department, located in Basel, Switzerland. We are seeking an independent and highly motivated researcher to advance our understanding of the mechanisms underlying the progression of inflammatory bowel diseases (IBD).Specifically, the research project will aim at investigating the role of T cell plasticity in maintaining intestinal homeostasis and in the development of chronic and tissue-damaging intestinal inflammation. In addition the relationship between T cell plasticity and intestinal microbiota will be a central element of this project. Profile:To cover for a maternity leave, we are looking for a scientist with education in immunology (PhD are preferred, Master or Post Doc are considered). This person needs to have experience in human immunology, cell biology and flow cytometry. Please note experience in human immunology is a must.General Information:• Start date: ASAP• Latest possible start date: 1 month notice period max• End date: 9 months duration• Extension: possible• Workplace: Basel• Workload: 100%• Remote/Home Office: Onsite needed, certificate will be required. Mostly onsite.• Travel: No• Team: Around 3 peopleTasks & Responsibilities:• Develop methods for isolation of immune cells from blood and tissue;• Perform detailed immune phenotyping of cell populations of interest using multicolormulti-color flow cytometry;• Perform sophisticated in vitro 3D cultures, including organoids, of human and mouse cells;• Investigate the impact of bacterial isolates and/or metabolites on host immune, epithelial and stromal cells;• In collaboration with data scientists, analyze multi omics data sets including scRNAseq, TCRseq, 16Sseq,metabolomics and identify molecules to be tested in vitro;• Carry out in vivo studies to further mechanistic understanding;• Form close collaborative relationships with other scientists within the Immunology Incubator, I2O Department andtechnical teams in other functions.Must Haves:• Min Master, preference on PhD in immunology (*****)• Profound understanding of human immunology, mucosal immunity and T cell biology. (*****)• Extensive experience with state-of-the-art flow cytometry, including FACS. (*****)• Track record of hands-on experience with isolation and cultivation of human immune cells. (*****)• Experience with in vivo models of inflammation is a plus.• Experience in data analysis using R or Python is a plus.• You have very good interpersonal and communication skills, are able to build good working relationships and are anoutstanding teammate.• Your experience and investigative attitude allow you to work independently, to design, perform and interpretexperiments and to embark on new scientific methodologies.• You published as a leading author in top-tier journals.• You have a strong team spirit, and you like to work in international teams• Your excellent English skills, written and spoken, complete your profile.
    • vaud, genève
    • temporary
    Do you have a first experience with R&D in the biopharma/biotech industry ? Would you like to continue your development in that direction ? If you replied “yes” to both those questions, I suggest you read the following description!For one of our clients, specialised in biotechnology and based in the Vaud canton, we are looking for a Specialist Scientist Clinical Pharmacology and Immunology for a contract until the end of the year 2022.Your tasks:Responsible for bioanalytical support of biosimilar development programs, with a particular focus on PK and immunogenicityOverseeing the compliance and scientific integrity of outsourced bioanalytical work for biosimilar development programsResponsible for Bioanalytics e2e procurement processCoordinates CROs or internal bioanalytical resources supporting early Product Development with regards to PK and immunogenicity method development, validation and sample analysis.Collaborate with clinical development and other relevant stakeholders to define pharmacology and immunology assessments required for the clinical development of a biosimilar projectLiaise with external consultants (e.g. pharmacologists) to gather required information and expertiseCollaborate with clinical operations to ensure adequate PK/PD and immunogenicity sample collection, management, handling and shipmentProvide expertise on data transfer, reconciliation and work with clinical operations and other internal stakeholders during the execution of clinical studiesIdentify and oversee bioanalytical laboratories for PK/PD and immunogenicity sample analysisRequest, review and manage contracts with bioanalytical laboratoriesReview and comment method development, validation and sample analysis plans and reports in terms of science and regulatory compliance. Supports data interpretation and integrationWork with project management to align timelines and budget with the overall development planContribute to bioanalytical laboratory oversight by performing regular visits and summarize outcome in reportsCoordinate and guide the activities of the bioanalytical laboratories during the execution of clinical studiesMonitor shipments and track stocks of critical reagents at bioanalytical laboratoriesOn bioanalytical and clinical pharmacology and immunology topics, contribute to regulatory submissions and briefing booksYour profile:Advanced scientific degree (PhD, MD or equivalent)Minimum 2-4 years’ experience in R&D in biopharma/biotech industryExperience in providing scientific oversight for bioanalytical projects placed at CROsExperience in bioanalytical sciences in e.g. preclinical / clinical studies related to PK, immunogenicity or biomarker assays, diagnostic lab or central labGood knowledge of scientific best practices, GLP and basic knowledge in regulatory guidelinesHas preferably worked in a global organization in a field supporting or performing drug developmentFluency in English essential, both oral and written, other languages are an assetSo ? Seems interesting ? Give it a shot and apply now!
    Do you have a first experience with R&D in the biopharma/biotech industry ? Would you like to continue your development in that direction ? If you replied “yes” to both those questions, I suggest you read the following description!For one of our clients, specialised in biotechnology and based in the Vaud canton, we are looking for a Specialist Scientist Clinical Pharmacology and Immunology for a contract until the end of the year 2022.Your tasks:Responsible for bioanalytical support of biosimilar development programs, with a particular focus on PK and immunogenicityOverseeing the compliance and scientific integrity of outsourced bioanalytical work for biosimilar development programsResponsible for Bioanalytics e2e procurement processCoordinates CROs or internal bioanalytical resources supporting early Product Development with regards to PK and immunogenicity method development, validation and sample analysis.Collaborate with clinical development and other relevant stakeholders to define pharmacology and immunology assessments required for the clinical development of a biosimilar projectLiaise with external consultants (e.g. pharmacologists) to gather required information and expertiseCollaborate with clinical operations to ensure adequate PK/PD and immunogenicity sample collection, management, handling and shipmentProvide expertise on data transfer, reconciliation and work with clinical operations and other internal stakeholders during the execution of clinical studiesIdentify and oversee bioanalytical laboratories for PK/PD and immunogenicity sample analysisRequest, review and manage contracts with bioanalytical laboratoriesReview and comment method development, validation and sample analysis plans and reports in terms of science and regulatory compliance. Supports data interpretation and integrationWork with project management to align timelines and budget with the overall development planContribute to bioanalytical laboratory oversight by performing regular visits and summarize outcome in reportsCoordinate and guide the activities of the bioanalytical laboratories during the execution of clinical studiesMonitor shipments and track stocks of critical reagents at bioanalytical laboratoriesOn bioanalytical and clinical pharmacology and immunology topics, contribute to regulatory submissions and briefing booksYour profile:Advanced scientific degree (PhD, MD or equivalent)Minimum 2-4 years’ experience in R&D in biopharma/biotech industryExperience in providing scientific oversight for bioanalytical projects placed at CROsExperience in bioanalytical sciences in e.g. preclinical / clinical studies related to PK, immunogenicity or biomarker assays, diagnostic lab or central labGood knowledge of scientific best practices, GLP and basic knowledge in regulatory guidelinesHas preferably worked in a global organization in a field supporting or performing drug developmentFluency in English essential, both oral and written, other languages are an assetSo ? Seems interesting ? Give it a shot and apply now!

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